...synthesis of squalamine from methyl chenodeoxycholanate

来自 : www.irgrid.ac.cn/handle/1471x/ 发布时间：2021-03-24

热门A short and highly stereoselective synthesis of squalamine from methyl chenodeoxycholanate

文献类型：期刊论文

作者Zhang DH(张冬辉); Cai F(蔡峰); Zhou XD(周向东); Zhou WS(周维善)刊名Chin. J. Chem.出版日期2005卷号23期号:2页码:176-181ISSN号1001-604X其他题名从鹅去氧胆酸甲酯简短和高立体选择性合成角鲨多胺通讯作者周维善英文摘要A short and highly stereoselective synthesis of squalamine (1) was accomplished in 9 steps from easily available methyl chenodeoxycholanate (2). The advanced intermediate 7alpha,24R-dihydroxy-cholestan-3-one (9) was synthesized by using improved dehydrogenation of 4 followed by conjugate reduction and efficient asymmetric isopropylation of aldehyde 7 as key reactions.学科主题天然产物有机化学收录类别SCI原文出处http://dx.doi.org/10.1002/cjoc.200590176WOS记录号WOS:000226769000012公开日期2013-01-15源URL[http://202.127.28.38/handle/331003/11704]专题上海有机化学研究所_中科院天然产物有机化学重点实验室
推荐引用方式
GB/T 7714Zhang DH,Cai F,Zhou XD,et al. A short and highly stereoselective synthesis of squalamine from methyl chenodeoxycholanate[J]. Chin. J. Chem.,2005,23(2):176-181.张冬辉,蔡峰,周向东,&周维善.(2005).A short and highly stereoselective synthesis of squalamine from methyl chenodeoxycholanate.Chin. J. Chem.,23(2),176-181.张冬辉,et al.\"A short and highly stereoselective synthesis of squalamine from methyl chenodeoxycholanate\".Chin. J. Chem. 23.2(2005):176-181.
英文摘要 A short and highly stereoselective synthesis of squalamine (1) was accomplished in 9 steps from easily available methyl chenodeoxycholanate (2)...中国科学院机构知识库网格系统: A short and highly stereoselective synthesis of squalamine from methyl chenodeoxycholanate